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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLST
All Species:
20
Human Site:
T142
Identified Species:
33.85
UniProt:
P36957
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P36957
NP_001924.2
453
48729
T142
E
G
G
T
P
L
F
T
L
R
K
T
G
A
A
Chimpanzee
Pan troglodytes
XP_510068
453
48665
T142
E
G
G
T
P
L
F
T
L
R
K
T
G
A
A
Rhesus Macaque
Macaca mulatta
XP_001095138
454
48899
T143
E
G
G
T
P
L
F
T
L
R
K
T
G
A
A
Dog
Lupus familis
XP_537510
443
47545
G136
L
F
T
L
R
K
T
G
A
A
P
A
K
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2G2
454
48976
T143
E
G
G
T
P
L
F
T
L
R
K
T
G
A
A
Rat
Rattus norvegicus
Q01205
454
48907
T143
E
G
G
T
P
L
F
T
L
R
K
T
G
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012919
461
49264
K145
E
G
G
T
P
L
F
K
L
R
K
T
G
A
A
Frog
Xenopus laevis
NP_001080703
452
48982
V140
E
G
G
T
P
L
F
V
L
R
K
S
G
A
A
Zebra Danio
Brachydanio rerio
NP_958895
458
48679
K142
E
G
G
T
P
L
F
K
L
K
K
G
A
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392679
444
49066
S143
K
D
G
Q
T
V
K
S
G
Q
K
L
C
V
I
Nematode Worm
Caenorhab. elegans
Q19749
507
53448
I151
P
I
G
K
L
L
C
I
I
V
D
N
E
A
D
Sea Urchin
Strong. purpuratus
XP_781522
508
55019
K186
V
P
G
Q
Q
L
L
K
I
Q
V
S
A
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150636
446
48757
I147
T
P
G
T
K
V
A
I
I
S
K
S
A
Q
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19262
463
50412
E151
L
A
Q
V
E
P
G
E
A
P
A
E
G
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98
87.4
N.A.
92.5
92.9
N.A.
N.A.
72.8
75
73.1
N.A.
N.A.
54.2
27.6
55.7
Protein Similarity:
100
99.5
98.4
91.3
N.A.
96.2
96
N.A.
N.A.
79.3
83.8
82.5
N.A.
N.A.
66.4
44.1
67.5
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
93.3
86.6
66.6
N.A.
N.A.
13.3
20
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
93.3
93.3
73.3
N.A.
N.A.
40
26.6
33.3
Percent
Protein Identity:
N.A.
45.7
N.A.
N.A.
42.1
N.A.
Protein Similarity:
N.A.
61.3
N.A.
N.A.
58.5
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
8
0
15
8
8
8
22
65
58
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
15
% D
% Glu:
58
0
0
0
8
0
0
8
0
0
0
8
8
0
0
% E
% Phe:
0
8
0
0
0
0
58
0
0
0
0
0
0
0
0
% F
% Gly:
0
58
86
0
0
0
8
8
8
0
0
8
58
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
15
22
0
0
0
0
0
8
% I
% Lys:
8
0
0
8
8
8
8
22
0
8
72
0
8
0
8
% K
% Leu:
15
0
0
8
8
72
8
0
58
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
15
0
0
58
8
0
0
0
8
8
0
0
0
8
% P
% Gln:
0
0
8
15
8
0
0
0
0
15
0
0
0
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
8
0
22
0
8
0
% S
% Thr:
8
0
8
65
8
0
8
36
0
0
0
43
0
0
0
% T
% Val:
8
0
0
8
0
15
0
8
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _